INF6500EN - Immunology of infection and vaccines

Course description

This graduate course examines how the immune system defends against pathogens and how vaccines harness that defense to prevent disease, with attention to the evidence behind each. Students analyze innate and adaptive immunity, antibody and cell-mediated responses, immunological memory, and microbial evasion. The course critically evaluates vaccine types, including live attenuated, inactivated, subunit, mRNA, and vector vaccines, along with adjuvants, combination vaccines, herd immunity, and vaccine failure. Students appraise vaccine development, clinical trials, manufacturing, regulation, and the policy decisions that bring new vaccines into national programs. They assess how schedules, special populations, safety monitoring, and communication about public concerns shape immunization success. Through case analysis and scholarly discussion, learners develop informed judgment about vaccines for diseases such as polio, measles, influenza, HPV, and COVID-19. Throughout, the course integrates immunology with Christian convictions about human dignity and healing, equipping ministry and health leaders to serve vulnerable communities across diverse cultural settings.

How this course benefits students

Graduate students gain advanced understanding of how the immune system recognizes and defeats pathogens and why vaccines are among the most effective health tools. They learn to appraise the evidence for vaccine effectiveness and safety, to evaluate how vaccine types differ, and to assess how immunization programs protect communities. This knowledge supports leadership in medicine, public health, laboratory science, biotechnology, humanitarian relief, and mission organizations. Students strengthen capacity to interpret research, evaluate policy, and communicate about vaccines responsibly. For leaders serving in under-resourced settings, the course offers a framework for supporting immunization and building trust with families and health authorities.

Why this course is important

Vaccines have prevented more illness and death than almost any other medical advance, yet millions of children remain unprotected, and preventable diseases still claim lives. Outbreaks of measles, polio, and whooping cough return where coverage falls, and new threats such as COVID-19 test every national health system. Misinformation and mistrust can undermine protection even where vaccines are available. Advanced understanding of immunity and vaccination equips leaders to interpret scientific evidence, shape policy, answer questions with accuracy and patience, and advocate for those overlooked. Informed leaders are needed everywhere to help churches and mission organizations serve with competence, humility, and compassion.

Credit hours
3 hours
Subject area
Infectious Disease
Educational level
Master
Learning type
Instructional
Prerequisites
None
Upcoming terms
Pending
* Schedule subject to change. Please contact the Registrar's office with schedule questions.

How this course relates to missional core values

Biblically based

Scripture presents a God who creates, sustains, and heals life, who is concerned for the vulnerable, and who calls his people to love the neighbor. This course grounds the critical study of immunity and vaccination in that witness, recalling the Law’s concern for community health and Jesus’ ministry of healing. Students integrate theological reflection on the dignity of every image-bearer, wise stewardship of scientific knowledge, and the care owed to children and the most vulnerable.

Missionally driven

The missio Dei declares that God is on mission to redeem the world and sends his people into it. Preventable disease afflicts the communities to which the church is sent, and vaccines are among the most effective means of protecting them from harm. This course frames graduate study of immunity and vaccination as preparation for sent leaders who enter hurting places with compassion and competence, participating in God’s mission to heal, restore, and reconcile creation.

Contextually informed

Immunization succeeds or fails in context. Geography, infrastructure, cold-chain reliability, poverty, conflict, and community trust determine whether vaccines reach children and whether families accept them. Students analyze how national programs adapt schedules, delivery, and communication to local conditions and needs. Learners also evaluate why an approach that succeeds in one setting may fail in another. This attentiveness to place reflects the incarnation, in which God entered a particular place to meet people where they live.

Interculturally focused

Disease and immunization cross borders, languages, and cultures, and effective responses depend on mutual respect. Students examine how health beliefs, trust in institutions, and cultural views shape how communities understand and respond to vaccines. They evaluate why culturally sensitive communication and local knowledge are essential for acceptance. Drawing on the model of Christ who crossed boundaries to dwell among us, the course prepares leaders to serve alongside people of other cultures as partners and learners.

Practically minded

Knowledge of immunity matters only when it leads to action. This course emphasizes the practical logic of vaccination: evaluating how vaccines are developed, tested, and approved, how schedules and circumstances guide who is vaccinated and when, and how safety is monitored and concerns are addressed. Through case analysis and applied discussion, students examine how clinicians and public health workers plan, deliver, and explain immunization. They gain insight into what effective, sustainable, and compassionate programs require.

Experientially transformed

Learning in this course engages the whole person. Through case analysis and reflection, students encounter the human realities behind immunization: children protected from disease, parents weighing questions and hopes, and health workers reaching distant villages. These encounters invite students to examine assumptions, fears, and callings. As they consider the cost of service among the vulnerable, students are shaped by the Spirit toward humility, courage, and compassion, becoming leaders whose lives embody God’s love for neighbors.